Hepatitis C virus (Flaviviridae: Hepacivirus: Hepacivirus C): regulation of signaling reactions of innate immunity
نویسندگان
چکیده
منابع مشابه
Hepatitis C virus' initial encounters: mechanisms of innate immunity.
HCV is a single-stranded RNA virus that affects approximately 210 million people worldwide causing chronic disease in 80% of those infected. With the development of new models of study, and a better understanding of the innate immune response, the way this virus induces and evades an immune response at the beginning of the infection has started to be recognized as a critical stage for the devel...
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Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). Assignments into 14 Hepacivirus species (Hepacivirus A-N) and 11 Pegivirus species (Pegivirus A-K) are based on phylogenetic relationships and sequence distances between conserved regions e...
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Nowadays viral hepatitis is one of the most common and important causes of chronic liver disorders in the world. Extrahepatic manifestations of viral hepatitis consist a main part of the disease. The main viruses causing hepatitis include Hepatitis A, B and C viruses. Herein common skin manifestations in hepatitis C virus (HCV) are discussed. Chronic hepatitis causes skin disorders both directl...
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The precise role of adaptive immune responses in the clinical outcome of HCV infection is still only partially defined. Recent studies suggest that viral-host cell interactions during the acute phase of infection are essential for viral clearance or progression into chronic HCV infection. This review focuses on different aspects of the adaptive immune responses as determinants of the different ...
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Recent studies in humans and chimpanzees suggest that immunity can be induced to diminish the incidence of chronic hepatitis C virus (HCV) infection. However, the immunity that promotes viral recovery is poorly understood, and whether the breadth of this adaptive immunity is sufficient to overcome the substantial intergenotype antigenic diversity represents a final obstacle to demonstrating the...
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ژورنال
عنوان ژورنال: Problems of Virology
سال: 2021
ISSN: 2411-2097,0507-4088
DOI: 10.36233/0507-4088-2020-65-6-1